Case study · AI for science

Multimodal evidence across scales.

Scientific questions rarely live in one format. We explore systems that connect sequences, measurements, images, text, and experimental context while keeping provenance and uncertainty attached to every synthesis.

Status
Research direction
Central question
How can models connect evidence across modalities without erasing what makes each measurement distinct?
Evidence standard
Task-specific validation, strong baselines, provenance, and expert review.

Can one representation respect many kinds of evidence?

A biological observation can look different at the molecular, cellular, tissue, and organism level. Its meaning also depends on experimental design, controls, and measurement technology. Joining those views can make a problem more tractable, but only if the system preserves their context.

The goal is not to flatten diverse data into one confident answer. It is to help organize relationships, identify missing evidence, and generate testable next questions.

Connect modalities without losing provenance.

Represent

Preserve modality-specific structure.

Respect spatial, temporal, sequence, and experimental relationships before aligning representations.

Align

Use shared context carefully.

Connect related observations while keeping sample, assay, condition, and source metadata available.

Reason

Separate retrieval from inference.

Make clear which conclusion follows from supplied evidence and which is a model-generated hypothesis.

Test

Return questions to experiment.

Prioritize outputs that can be checked against held-out measurements, perturbations, or expert review.

Scientific usefulness needs task-specific proof.

This page describes broad research interests and does not announce a validated scientific or clinical result. Evidence should be matched to a clearly scoped question, evaluated on data separated by the relevant biological and experimental boundaries, and compared with meaningful baselines.

Validation

Held-out biological context

Split data in ways that test the claimed generalization—not merely random records from the same context.

Baselines

Value beyond simpler methods

Compare against domain tools, retrieval, and unimodal models before attributing gains to multimodality.

Uncertainty

Calibration and abstention

Measure whether confidence tracks reliability and whether the system can defer when evidence is thin.

Provenance

Traceable inputs and outputs

Keep data sources, transformations, and the basis for a generated hypothesis inspectable.

A coherent story can still be wrong.

Scientific datasets contain batch effects, confounding, missing context, and uneven representation. A model can produce plausible connections without causal support. Performance on one dataset does not establish transfer across populations, laboratories, assays, or biological scales.

Use boundary. The work described here is exploratory. It is not medical advice, a diagnostic system, a substitute for qualified scientific judgment, or a claim of validated discovery.